5th Down Fantasy

5th Down Fantasy

Week 6 fantasy football playbook

Studs, duds, sneaky DFS picks and more for each position (that matters) on your Week 6 fantasy football squad.

Justin Sablich's avatar
Justin Sablich
Oct 11, 2025
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Thanks again for being a loyal reader and subscriber! Keep reading for the latest fantasy football rankings, injury news, players trending up and down, and more. Best of luck in Week 6!


EDITOR’S NOTES

Best/worst matchups: Matchup rankings listed, other than WR, are courtesy of The Athletic’s Jake Ciely’s matchup rankings, which include his homemade metric, Adjusted Points Allowed (APA). WR rankings are based on WR/CB matchup ratings by fantasypoints.com.
Rankings: If viewing from email, clicking on the image will open the rankings in a new window. There are also links to the latest full rankings at the end of each individual chart.
DFS values: Pulled from our DFS Projections tool, with data courtesy of dailyfantasyfuel.com. “Value” projects how much return on investment a player will deliver, based on salary and projected performance.

Week 6 playbook: Quarterbacks

View all Week 6 player rankings.

🤕 Pain index

  • 🚫 Nope: Lamar Jackson (BAL)

  • ✅ Good to go: Jayden Daniels (WAS)

View latest NFL injury report

↕️ QB matchup breakdown

📈 Notable QBs with great matchups

  • Best - Jayden Daniels (WAS) vs. CHI

  • 2nd best - Sam Darnold (SEA) at JAC

  • 3rd best - Dak Prescott (DAL) at CAR

💪 Stud potential: Dak Prescott — He’s been red-hot, averaging over 30 fantasy points across his last two games (even without CeeDee Lamb). Now he gets a Panthers defense coming off of thrashings from Drake Maye and Tua Tagovailoa. Expect another high-end QB1 finish as Prescott continues his dominant run in a very favorable Week 6 matchup.

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